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AestheFill® PDLLA Injectable Collagen Biostimulator

AestheFill® PDLLA is an injectable collagen biostimulator based on poly-D,L-lactic acid (PDLLA), designed for gradual volume restoration and skin quality improvement.
A biodegradable polymer with predictable degradation ensures uniform collagen stimulation and natural results.
For professional use only.

✔ CE certified   ✔ MDR compliant

AestheFill® PDLLA is a next-generation injectable collagen biostimulator designed for gradual volume restoration and long-term skin rejuvenation.

The formula is based on poly-D,L-lactic acid (PDLLA) — a biodegradable polymer with an amorphous structure, ensuring predictable degradation and uniform collagen stimulation.

The product delivers a dual mechanism of action: it activates natural collagen production while progressively improving skin density, elasticity, and overall skin quality.

The microparticle structure facilitates suspension preparation and promotes even distribution within the tissues, contributing to stable and natural-looking results.

Brand (Бренд)

  • Product name: AestheFill® PDLLA
  • Category: Collagen Biostimulators / Biostimulator
  • Form: vial with lyophilized powder for suspension preparation
  • Active substance: PDLLA (Poly-D,L-lactic acid)
  • Product type: injectable collagen biostimulator
  • Technology: BPM (Biodegradable Polymer Microsphere)
  • Mechanism of action: stimulation of neocollagenesis
  • Structure: amorphous (controlled and uniform degradation)
  • Degradation: gradual and predictable
  • Effect: progressive volume restoration and skin quality improvement
  • Duration of effect: up to 2–3 years
  • Treatment areas: face, lower face, volumetric zones
  • Indications: correction of age-related changes and collagen stimulation
  • Status: Medical Device
  • Certification: CE certified (compliant with European standards)
  • Manufacturer: REGEN Biotech Inc. (South Korea)
  • Active substance: PDLLA (Poly-D,L-lactic acid)
  • Composition: biocompatible and biodegradable synthetic polymer
  • Sterility: sterile product, single-use
  • Biodegradation: gradual and predictable
  • Conditions of use: for use by qualified medical professionals only
  • Prescription status: subject to medical regulation depending on country
  • Shelf life: indicated on the original manufacturer packaging
  • Storage conditions: according to manufacturer instructions

Manufacturer and distributor emphasize that injectable procedures must be performed only by trained medical professionals with appropriate anatomical knowledge.

What is AestheFill®?
AestheFill® is an injectable collagen biostimulator based on PDLLA (Poly-D,L-lactic acid), designed for gradual volume restoration and skin quality improvement.

How does the product work?
After injection, PDLLA microspheres stimulate natural collagen production, leading to progressive skin structure improvement and natural volume enhancement.

What is the difference from traditional fillers?
Unlike hyaluronic acid fillers, AestheFill® does not provide immediate volume but works through gradual collagen stimulation.

When are results visible?
Results develop progressively over several weeks and improve as collagen production increases.

How long do results last?
Results may last up to 2–3 years depending on individual patient factors.

Which areas can be treated?
Suitable for volumetric facial areas, including the lower face and areas with significant volume loss.

What is special about PDLLA?
PDLLA has an amorphous structure, ensuring uniform degradation and predictable collagen stimulation.

Is preparation required before use?
Yes, the product must be reconstituted before injection to obtain a stable suspension.

Who is the product suitable for?
Suitable for patients with signs of aging, reduced skin density, and volume loss.

Can it be combined with other treatments?
Yes, it can be used in combined aesthetic protocols at the practitioner’s discretion.